NMAT Biology Review: NMAT Study Guide
The Biology section of the NMAT (National Medical Admission Test) is one of the most content-heavy parts of the exam. It tests not only memorization but also your ability to understand biological concepts, interpret data, and apply knowledge to unfamiliar situations. A strong performance in Biology can significantly improve your overall NMAT percentile rank, especially since many medical schools in the Philippines place considerable weight on this section.
This NMAT Biology Review is designed as a comprehensive study guide, covering all major topics you are likely to encounter. It focuses on clarity, exam relevance, and strategic preparation rather than unnecessary detail.
Overview of the NMAT Biology Section
The NMAT Biology subtest evaluates foundational knowledge expected of pre-med students. Questions are typically multiple-choice and may include diagrams, experimental setups, tables, and short passages.
Key characteristics of the Biology section include:
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Broad topic coverage rather than deep specialization
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Emphasis on core concepts and relationships
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Frequent use of visual interpretation (graphs, charts, illustrations)
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Application-based questions rather than pure recall
To succeed, you must understand how biological systems work, not just memorize definitions.
Cell Biology and Cell Structure
Cell biology is a high-yield topic in the NMAT. Questions often focus on structure-function relationships within the cell.
Key areas to review:
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Prokaryotic vs. eukaryotic cells
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Plant vs. animal cells
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Cell membrane structure (fluid mosaic model)
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Organelles and their functions
You should be able to explain the roles of major organelles such as the nucleus, mitochondria, ribosomes, endoplasmic reticulum, Golgi apparatus, lysosomes, chloroplasts, and vacuoles. Understanding how structure relates to function is more important than memorizing isolated facts.
Transport mechanisms across the cell membrane are also frequently tested, including diffusion, facilitated diffusion, active transport, osmosis, endocytosis, and exocytosis.
Cell Biology and Cell Structure: NMAT Biology Review
Biomolecules and Enzymes
This topic bridges Biology and Chemistry and is commonly tested in the NMAT.
Important biomolecules include:
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Carbohydrates
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Lipids
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Proteins
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Nucleic acids
You should know the basic structure, building blocks, and functions of each group. For proteins, understand the levels of structure (primary to quaternary) and how structure determines function.
Enzymes are especially important. Review:
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Enzyme specificity
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Lock-and-key vs. induced-fit models
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Factors affecting enzyme activity (temperature, pH, substrate concentration, inhibitors)
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Competitive vs. non-competitive inhibition
NMAT questions often test conceptual understanding, such as predicting what happens to enzyme activity under altered conditions.
Biomolecules and Enzymes: NMAT Biology Review
Cell Cycle and Cell Division
The NMAT frequently includes questions about cell division, especially mitosis and meiosis.
Key concepts to master:
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Stages of the cell cycle (G1, S, G2, M)
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Regulation of the cell cycle
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Checkpoints and their significance
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Differences between mitosis and meiosis
For mitosis, focus on the purpose and outcomes rather than memorizing every microscopic detail. For meiosis, understand genetic variation, crossing over, independent assortment, and how chromosome number is reduced.
Questions may also involve identifying stages based on diagrams or explaining the consequences of errors in cell division.
Cell Cycle and Cell Division: NMAT Biology Review
Genetics and Heredity
Genetics is a major component of the NMAT Biology section and often includes problem-solving questions.
Core topics include:
You should also understand:
Molecular genetics concepts such as DNA replication, transcription, and translation are also important. Be able to identify the roles of DNA, mRNA, tRNA, ribosomes, and enzymes involved in protein synthesis.
Genetics and Heredity: NMAT Biology Review
Molecular Biology and Gene Expression
This topic focuses on how genetic information is stored, expressed, and regulated.
Important areas include:
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DNA structure and base pairing
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Semi-conservative DNA replication
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RNA types and functions
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Central dogma of molecular biology
Questions may test your understanding of mutations, including point mutations, insertions, deletions, and frameshift mutations. You should also know how mutations can affect protein structure and function.
Basic gene regulation concepts, such as operons (especially the lac operon), may appear in simplified form.
Photosynthesis and Cellular Respiration
These topics test your understanding of energy flow in biological systems.
For photosynthesis, focus on:
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Light-dependent reactions
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Light-independent reactions (Calvin cycle)
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Role of chlorophyll
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Inputs and outputs of each stage
For cellular respiration, review:
Rather than memorizing every intermediate molecule, understand where each process occurs, what goes in, what comes out, and why each step is important.
Human Anatomy and Physiology
Human biology is a central part of NMAT Biology and often appears in applied questions.
Major systems to review include:
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Digestive system
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Respiratory system
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Circulatory system
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Nervous system
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Endocrine system
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Excretory system
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Reproductive system
You should understand how these systems function individually and interact with one another. Hormonal regulation, feedback mechanisms, and homeostasis are commonly tested concepts.
Questions may involve identifying organs, tracing pathways (such as blood flow or nerve impulses), or predicting outcomes when a system is disrupted.
Plant Biology
Plant biology appears less frequently than human biology but should not be ignored.
Key topics include:
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Plant tissues and organs
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Transport systems (xylem and phloem)
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Transpiration
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Plant hormones (auxins, gibberellins, cytokinins, ethylene, abscisic acid)
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Plant responses to stimuli
You should understand how water and nutrients move through plants and how plants regulate growth and development.
Ecology and Environment
Ecology questions test your understanding of interactions among organisms and their environment.
Important concepts include:
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Levels of ecological organization
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Food chains and food webs
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Energy flow and trophic levels
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Biogeochemical cycles (carbon, nitrogen, water)
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Population growth and limiting factors
Environmental issues such as pollution, conservation, and sustainability may appear in a conceptual or data-based format.
Evolution and Natural Selection
Evolution is a foundational biological concept and may appear directly or indirectly.
Key ideas to understand:
Questions often test your ability to interpret evolutionary scenarios rather than recall historical details.
Common NMAT Biology Question Types
NMAT Biology questions typically fall into several categories:
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Conceptual questions testing understanding
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Diagram-based identification questions
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Data interpretation questions
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Application and reasoning questions
Practicing these question types will improve your speed and accuracy during the exam.
Study Strategies for NMAT Biology
To prepare effectively for NMAT Biology:
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Focus on understanding concepts rather than memorization
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Use diagrams and flowcharts to visualize processes
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Practice answering questions under time pressure
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Review mistakes carefully to identify weak areas
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Integrate Biology with Chemistry and Physics where concepts overlap
Consistency and active recall are more effective than last-minute cramming.
Final Thoughts on NMAT Biology Preparation
NMAT Biology can seem overwhelming due to the wide range of topics, but it is highly manageable with structured preparation. The exam rewards conceptual clarity, logical reasoning, and familiarity with fundamental biological principles.
By mastering the core topics outlined in this NMAT Biology Review and practicing regularly, you can significantly improve your confidence and performance on test day. Biology is not just about facts; it is about understanding life processes, and that understanding is exactly what the NMAT aims to measure.
FAQs (Frequently Asked Questions)
How difficult is the NMAT Biology section compared to other NMAT subtests?
The NMAT Biology section is often considered one of the most content-heavy parts of the exam because it covers a wide range of topics, from cell biology to human physiology and ecology. However, the difficulty is usually moderate if you have a strong foundation in basic concepts and you practice applying them. Compared to Physics or Quantitative Ability, Biology may feel more memory-based, but many questions still require reasoning, interpretation of diagrams, and understanding cause-and-effect relationships. With consistent review and practice, Biology becomes very manageable.
What are the most high-yield Biology topics for NMAT preparation?
High-yield topics typically include cell structure and function, biomolecules and enzymes, genetics and heredity, DNA/RNA and protein synthesis, cellular respiration and photosynthesis, and human anatomy and physiology (especially circulatory, respiratory, endocrine, nervous, and reproductive systems). Basic ecology and evolution also appear and can be easy points if you study them well. If your time is limited, prioritize topics that combine conceptual understanding with common exam-style questions, such as genetics problems and physiology regulation mechanisms.
Do I need to memorize every detail, or should I focus on understanding concepts?
Conceptual understanding should be your top priority. While Biology involves terminology and facts, NMAT questions often test whether you understand how processes work rather than whether you can recite definitions. For example, instead of memorizing all steps of the Krebs cycle, you should know its purpose, where it occurs, and the types of outputs it produces. The same applies to photosynthesis, enzyme activity, and physiology systems. Memorization is useful for key terms, but understanding helps you answer unfamiliar or application-based questions.
How should I study Biology if my background is weak?
If your Biology foundation is weak, start by rebuilding basics through a structured review. Begin with cell biology, biomolecules, and genetics because these concepts support many other topics. Use simple textbooks, review notes, or video lessons to understand core ideas, then immediately practice questions to reinforce learning. Study in small, consistent sessions rather than long, irregular ones. Focus on mastering one topic at a time and avoid jumping randomly between chapters. Track your mistakes and revisit weak areas weekly to ensure progress.
How important are diagrams, graphs, and data interpretation in NMAT Biology?
Visual interpretation is very important. Many Biology questions include diagrams of cells, organ systems, stages of mitosis or meiosis, pedigrees, and ecological relationships. Some questions present graphs showing enzyme activity, population growth, or physiological responses, and you must interpret trends rather than recall facts. To prepare, practice reading charts quickly and translating visuals into biological meaning. When reviewing, draw your own diagrams of key processes like respiration, photosynthesis, and hormonal feedback loops. This helps improve recall and exam speed.
What is the best way to practice Genetics for NMAT?
Genetics improves most through problem practice. Start with basic Mendelian inheritance and master Punnett squares for monohybrid crosses before moving to dihybrid crosses. Then include non-Mendelian patterns such as incomplete dominance, codominance, multiple alleles, and sex-linked inheritance. Practice interpreting pedigrees and identifying likely genotypes based on family patterns. When you get a question wrong, write the correct reasoning step-by-step and identify what confused you (such as allele notation, probability, or trait type). Over time, genetics becomes one of the easiest scoring areas.
How deep should I study human anatomy and physiology for the NMAT?
You should study physiology at a functional level, focusing on how systems work and interact rather than memorizing every anatomical detail. Know the major organs of each system and the pathway of processes such as digestion, gas exchange, blood circulation, nerve signaling, and hormone regulation. Homeostasis is especially important, including feedback mechanisms like blood sugar control (insulin and glucagon) and temperature regulation. Understanding the “why” behind each system’s role will help you answer application questions more effectively than memorizing organ lists.
Should I study plant biology and ecology, even if they seem less common?
Yes. Plant biology and ecology may appear less frequently than genetics or human physiology, but they can be easy points because the concepts are straightforward once understood. Review transport in plants (xylem and phloem), transpiration, photosynthesis basics, and plant hormones at a high level. For ecology, understand food webs, trophic levels, population growth patterns, and cycles like carbon and nitrogen. These topics often appear as conceptual or data interpretation questions, which means strong understanding can help you answer quickly and accurately.
How can I improve my speed in answering Biology questions on the NMAT?
Speed comes from familiarity and practice. Build a strong foundation first, then do timed practice sets that mimic NMAT pacing. Train yourself to identify the question type quickly: recall, diagram interpretation, data analysis, or application. For long questions, read the last line first to understand what is being asked, then scan the passage for relevant information. Avoid overthinking; many Biology questions are designed to be solved using basic principles. Regular timed drills, along with reviewing mistakes, will naturally improve your speed and confidence.
What should my final week of NMAT Biology review look like?
In the final week, focus on consolidation rather than learning entirely new content. Review your weakest topics based on past practice tests, then revisit high-yield areas such as genetics, enzymes, and physiology regulation. Use active recall: quiz yourself, explain concepts out loud, and solve mixed question sets. Do at least one full timed Biology practice session to strengthen endurance and pacing. Keep notes short and practical, focusing on mistakes, key processes, and common traps. Prioritize rest and consistency so you arrive on test day clear-headed and prepared.