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Writing a medical research paper is never an easy task, even for native English speakers. For non-native speakers, the challenges are often doubled: mastering technical medical terminology, expressing ideas clearly, and meeting international journal standards. However, with the right approach, strategies, and tools, non-native authors can produce high-quality papers that are publishable in respected journals.
This guide offers practical tips to help non-native speakers navigate the complex process of writing medical research papers effectively.
Most journals expect research papers to follow the IMRaD format—Introduction, Methods, Results, and Discussion. Becoming familiar with this structure helps you organize your ideas logically and write with more confidence.
Introduction: Provide background, define the research gap, and state your hypothesis or objectives.
Methods: Explain how the study was conducted, including participants, materials, procedures, and statistical analysis.
Results: Present findings in a clear, objective way with tables, graphs, and figures. Avoid interpretation here.
Discussion: Interpret the results, explain their significance, compare with previous research, and highlight limitations.
Conclusion: Summarize the key findings and implications.
Non-native speakers often try to write everything at once. Instead, approach each section separately to reduce stress and ensure clarity.
Medical English is highly specific, and using the correct terms is crucial. For non-native speakers, mistakes in terminology can confuse reviewers and reduce credibility.
Tips:
Read extensively: Regularly read international journals such as The Lancet, NEJM, or JAMA to learn how terms are used in context.
Build a glossary: Keep a personal glossary of medical terms you frequently encounter.
Avoid literal translation: Translating directly from your native language often creates awkward phrasing. Instead, search for published English articles in your field to see accepted terminology.
Use consistent terminology: Don’t switch between synonyms (e.g., “myocardial infarction” and “heart attack”) unless context requires it.
Clarity is more important than complicated vocabulary. Many non-native authors mistakenly believe that using long, complex words makes their paper more professional. In reality, reviewers prefer simple, precise, and direct language.
Examples:
Instead of “It is clearly evident that the patient exhibited symptoms which were indicative of myocardial infarction,” write: “The patient showed symptoms of myocardial infarction.”
Instead of “Due to the fact that,” simply write: “Because.”
Strategies for clarity:
Write short sentences (15–20 words).
Use active voice when possible: “We conducted a survey” is clearer than “A survey was conducted.”
Limit jargon to what is necessary for the field.
Even strong researchers struggle with grammar. Some common pitfalls include:
Articles (a, an, the): Many languages do not use articles, so errors are common. Remember:
Use a/an for something general: “a patient was admitted.”
Use the for something specific: “the patient in bed 3.”
Subject-verb agreement:
Incorrect: “The results shows a clear pattern.”
Correct: “The results show a clear pattern.”
Tense usage:
Methods: usually past tense (“We measured blood pressure”).
Results: past tense (“The data indicated”).
Discussion: mix of present and past tense depending on context.
Prepositions: These often vary between languages. Always check phrases in published papers (e.g., “associated with,” not “associated to”).
Good research papers guide the reader smoothly from one idea to the next. To achieve this, focus on transitions and logical connections.
Techniques:
Use linking words: therefore, however, in contrast, as a result.
Ensure each paragraph begins with a clear topic sentence.
Keep one main idea per paragraph.
Example of improved flow:
Weak: “We tested 200 patients. The results were analyzed. There were differences between groups.”
Stronger: “We tested 200 patients, and after analyzing the results, we found significant differences between groups.”
For non-native speakers, figures and tables are powerful tools. They help reduce the amount of complex text and make findings clearer.
Tips:
Label all tables and figures clearly.
Use standard abbreviations (e.g., HR for hazard ratio).
Ensure captions are self-explanatory so readers understand the figure without referring back to the main text.
Improper citation is a common reason for rejection. Learn the style guide of your target journal (e.g., Vancouver style is common in medicine).
Advice:
Use reference management software such as EndNote, Mendeley, or Zotero.
Double-check that in-text citations match the reference list.
Avoid over-citing local or non-English sources; prioritize widely recognized journals.
Non-native speakers benefit greatly from external feedback. Before submission:
Ask colleagues fluent in English to review the draft.
Consider professional editing services specializing in medical manuscripts.
Join academic writing groups or workshops where peers can exchange feedback.
Peer input not only improves language but also helps identify unclear explanations or logical gaps.
Modern technology can be a strong ally in medical writing:
Grammarly or LanguageTool: For grammar and spelling checks.
ChatGPT or AI writing assistants: For paraphrasing, clarity improvement, or generating alternative sentence structures (but always fact-check results).
PubMed: For studying how top journals phrase their findings.
Google Scholar: To find recent papers with relevant expressions.
Remember, these tools are helpers—not substitutes—for your own critical thinking and discipline.
Scientific writing style in English often differs from that in other languages:
English emphasizes brevity and clarity over formality.
Direct statements are valued; indirect or overly polite expressions can seem vague.
Reviewers expect transparency—report limitations openly rather than hiding them.
Adapting to this cultural writing style is as important as mastering grammar.
Before sending your paper to a journal, ask yourself:
Is the paper structured according to IMRaD?
Are all terms consistent and accurate?
Have I avoided overly complex or literal translations?
Are tables and figures properly labeled and referenced?
Have colleagues or editors reviewed the manuscript?
Does the reference list follow the required style guide?
Have I checked for grammar, spelling, and formatting errors?
Writing a medical research paper as a non-native speaker is challenging but achievable. The key is preparation: understanding the structure, mastering terminology, writing clearly, and seeking feedback. With practice and persistence, non-native authors can produce polished, impactful papers that meet international publishing standards.
Instead of viewing language as a barrier, consider it an opportunity. By combining medical expertise with strong writing skills, non-native speakers can contribute valuable perspectives to global medical knowledge.
The most common structure is IMRaD: Introduction, Methods, Results, and Discussion, often followed by a concise Conclusion and standard sections for Acknowledgments, Conflicts of Interest, Funding, Data Availability, and References. Using this order helps reviewers locate key information quickly and improves the clarity of your manuscript.
Follow a simple three-step flow: (1) Brief context of the clinical problem, (2) the gap in current evidence, and (3) your study objective or hypothesis. Keep sentences short and avoid idioms. Example: “Hypertension is prevalent worldwide. However, evidence in adults under 30 is limited. We aimed to estimate the prevalence and associated factors in young adults.”
Use past tense for Methods and Results (“we enrolled,” “we found”), present or present perfect when describing established knowledge in the Introduction and Discussion (“hypertension is,” “studies have shown”), and present tense for general conclusions (“these findings suggest”). Maintain consistency within each section.
Do not translate expressions word-for-word from your native language. Instead, model your phrasing on sentences from high-quality journals in your field. Keep a personal phrase bank (e.g., “was associated with,” “did not differ significantly”) and reuse those patterns to stay consistent.
Report the study design, setting, eligibility criteria, sample size determination, variables and definitions, measurement tools (with model/vendor if relevant), data collection procedures, statistical tests (including assumptions and software), and ethical approvals. Provide enough detail so another researcher could replicate your work.
Report primary outcomes first, then secondary outcomes. Avoid interpretation in this section. Use tables and figures to show key numbers (effect estimates, confidence intervals, exact p-values). Refer to each table/figure in the text and avoid repeating every number from them; emphasize the most important findings.
Use a four-part structure: (1) brief summary of the main finding in one or two sentences, (2) comparison with prior studies and plausible mechanisms, (3) strengths and limitations (be candid and specific), and (4) practical implications and future research. End with a clear, non-speculative take-home message.
Use standard terms from recognized guidelines and leading journals. Define abbreviations at first use in the Abstract and again in the main text if required (e.g., “acute myocardial infarction (AMI)”). Avoid uncommon or local abbreviations. Keep a consistent glossary for your team to prevent synonym switching.
Match your scope, study design, and audience with a journal’s aims and recent publications. Check acceptance of your article type, word limits, open access options, fees, and indexing. Review recent articles on similar topics to gauge fit. Avoid predatory journals that promise unrealistically fast decisions without rigorous peer review.
Use the journal’s required format (structured vs. unstructured). Include background (1–2 sentences), objective, design/setting/participants, main outcomes, key results with effect sizes and 95% CIs, and a concise conclusion. Avoid new abbreviations and claims not supported by the results.
Each table or figure should answer one question: comparisons, trends, or relationships. Use clear titles, footnotes for abbreviations, and consistent decimal places. Ensure figures are legible at journal-required DPI and dimensions. Do not decorate; prioritize readability and accurate data presentation.
Provide effect sizes (e.g., mean differences, odds ratios, hazard ratios) with 95% confidence intervals and exact p-values. State statistical tests and assumptions, and mention how missing data were handled (e.g., complete-case analysis, multiple imputation). Avoid overstating significance; discuss clinical relevance alongside statistical results.
State IRB/ethics approval and informed consent when applicable. Register clinical trials prospectively and include the registration number. Follow relevant reporting checklists (e.g., CONSORT, STROBE, PRISMA, CARE) and upload completed checklists if required. Transparency strengthens credibility and expedites review.
Make one to two sentences that directly reflect your primary outcome and its practical meaning. Avoid introducing new data or broad speculation. Example: “In adults under 30, hypertension prevalence was 9% and associated with higher BMI. Early screening initiatives could be beneficial.”
Adopt a revise-by-layers approach: first fix structure and logic, then simplify sentences, then correct grammar, and finally polish vocabulary. Read your paper aloud to check rhythm and clarity. Maintain a personal style guide for preferred phrases, units, and capitalization rules.
Use reference managers (Zotero, EndNote, Mendeley) for citations; grammar checkers for typos and article usage; and discipline-specific term banks for standardized wording. AI writing assistants can suggest clearer phrasing, but you must verify facts, preserve authorship integrity, and follow journal policies on AI-assisted writing.
Follow the journal’s style (often Vancouver). Ensure every in-text citation appears in the reference list and vice versa. Prefer recent, peer-reviewed, and authoritative sources. Check all DOIs, page numbers, and author names. Avoid excessive self-citation and confirm that key prior studies are acknowledged.
In one page, state the article title and type, the research question and why it matters to the journal’s readers, the main findings, novelty, and confirmations that the work is original, not under consideration elsewhere, and approved by relevant ethics boards. Mention any related preprints or prior postings if applicable.
Remove filler phrases, replace nominalizations with verbs (“performed an analysis” → “analyzed”), and combine short, related sentences. Keep one idea per sentence and one purpose per paragraph. Target 15–20 words per sentence and avoid duplicate statements already shown in tables.
Be specific and transparent. Explain potential biases (selection, measurement, confounding), sample size constraints, generalizability, and missing data. If feasible, quantify their likely impact. State how future studies could address these issues. Honest limitations strengthen reviewer trust.
Follow criteria such as substantial contribution, drafting or critical revision, final approval, and accountability. Use a contributorship taxonomy (e.g., CRediT) if the journal requests it. Disclose funding, conflicts of interest, and the role of sponsors. Add data availability statements and acknowledge non-author contributors properly.
Respond politely and point-by-point in a separate document. Quote or summarize each comment, state what you changed with manuscript line references, and justify respectfully when you disagree. Keep a professional tone and provide additional analyses or sensitivity checks when reasonable.
Self-plagiarism is generally discouraged, even if you are the original author. Methods wording sometimes overlaps across related studies, but you should still rephrase and cite your prior work where appropriate. Always follow the journal’s plagiarism policy and use originality checks before submission.
Medical English: Complete Guide for Healthcare Professionals, Students, and Global Communication